Whitepaper

Predicting Novel Crosstalks in Oncology Using evidence-rich knowledge graphs

Key Highlights

  • From broken target discovery workflows to novel target identification in NEPC: How disease-specific knowledge graphs uncover biology that traditional databases miss.
  • How a disease-specific knowledge graph uncovered a novel NEPC target where conventional target discovery platforms found only known biology.
  • Why rare cancer target discovery fails and how causal, evidence-backed knowledge graphs can reveal hidden therapeutic opportunities.
  • Building disease-specific causal knowledge graphs to identify novel targets in data-sparse cancers beyond co-occurrence-based approaches.
  • See how an AI-powered causal knowledge graph identified EHMT2 as a novel target in NEPC after standard databases reached a dead end.
  • Rethinking target discovery for rare cancers with disease-specific, evidence-backed knowledge graphs.
  • Beyond co-occurrence: Uncovering novel drug targets in rare cancers with disease-specific knowledge graphs.
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