Webinar
Upcoming Webinar
In collaboration with

De-risking Autoimmune Clinical Trials with Agentic AI

Translating Biomarkers and Patient-reported outcomes into patient benefit

What the AI Co-Scientist Paper Actually Demonstrates for Biologists and Data Scientists

September 30, 2025
10:30 AM PST / 1:30 PM EST

One of the reasons trials for Autoimmune indications often fail is that endpoints don’t necessarily track patient-related outcomes.

Conditions like Rheumatoid Arthritis, Lupus, T1 Diabetes, and Multiple Sclerosis generate vast evidence - cytokines, imaging, digital measures. They also have significant impact on patient quality of life, as measured by PROs - Patient related outcomes - such as fatigue, pain, mobility, stool frequency.

However, biomarkers and PROs are siloed and inconsistently defined. Translational teams move slowly, protocols churn, and designs lean on incomplete precedent.

Regulators are now recognizing PROs as pivotal endpoints - sometimes even driving approvals or label changes.

In this webinar, we talk about the opportunity of linking PROs with biomarkers to define composite endpoints and cohorts that reflect patient benefit and regulatory expectations.

This webinar will show how Polly Xtract’s agentic AI unifies autoimmune trial evidence into a single, source-linked dataset. By connecting PROs with biological markers, you’ll see how to benchmark across autoimmune diseases, identify composite endpoints, and design trials set up to capture meaningful signal before decisions harden.

Register Now
Please enter only business email id.
Thank you for registering.

Please check your inbox for further details to join this webinar.
Oops! Something went wrong while submitting the form.
Registrations are closed!
Meet the Expert of this discussion
Devan Moodley
Head of Translational Sciences (ex-Abata)
Sachin Gupta
Senior Scientific Manager, Elucidata

Real-World Applications We’ll Cover

  • Scaling clinico-genomic data integration: Large pharmaceutical organizations working with external data providers used Polly to build interoperable clinico-genomic data products 6x faster.
    Although purchased datasets are often labeled as "clean," they still lack interoperability—Polly's pipelines bridge this gap with robust integration and harmonization.

  • Information Retrieval: Drug safety monitoring teams used Polly's Knowledge Graph powered co-scientist to conversationally retrieve the right cohorts & assess drug response—cutting discovery time by 70%.

Register now
Join us for a behind-the-scenes look at a Multi-agent AI system that achieves:
  • 93% recall across 23 key metadata fields including tissue, disease, cell line, donor ID, and treatment.
  • Outperformance of GPT-4.1 single-pass prompting on accuracy, F1 score, and traceability.
  • Curation of 4652 samples from 78 GEO datasets in days instead of weeks.
  • 4x reduction in manual effort equivalent to replacing a 3-person expert team working for 1 month.
  • Human-level accuracy, with 100% concordance on disease and 97% on gender based on CellxGene benchmarks.
  • Traceable records with field-level evidence attribution and confidence scores.
Register for our webinar to see how the Agentic AI system fits into scalable data workflows.

What You’ll Learn

  • Build precedent sets: How to scout autoimmune trials across conditions like RA, Lupus, MS, T1D.
  • Live demo: Polly Xtract structures unstructured trial evidence (biomarkers, PROs, endpoints, safety) with clickable provenance.
  • Benchmark endpoints: Normalize outcomes to compare candidate programs against prior RA and lupus trials.
  • AI-guided trial design: Agents recommend cohorts, exclusion criteria, and PRO–biomarker composites prioritized by regulators.
  • Operationalization: Package insights for IND/protocol review and regulatory queries with full traceability.
Register now
Meet the Expert of this discussion
Devan Moodley
Head of Translational Sciences (ex-Abata)
Sachin Gupta
Senior Scientific Manager, Elucidata
Meet the Expert of this discussion
Devan Moodley
Head of Translational Sciences (ex-Abata)
Sachin Gupta
Senior Scientific Manager, Elucidata
What Sets polly KG Apart
Natural language querying with reasoning on
the roadmap
Cross-species graphs built from both proprietary
and public data
Custom scoring logic and domain-specific
ontology support
Seamless integration with internal tools, platforms,
and security frameworks
Who Should Attend
Translational Scientists and Discovery Leads
Computational Biologists and Data Scientists
Platform Owners, heads of R&D IT
Innovation and AI Strategy Teams
Who Should Attend
Translational Scientists and Discovery Leads
Data Science & Informatics Teams
Computational Biologists and R&D IT Leaders
Innovation & AI Strategy Teams

Why This Matters for Biomedical Researchers

If you’re working with complex biological data, you may be asking:

  • Can generative AI truly assist in scientific reasoning, not just data analysis?

  • What does it mean for hypothesis generation, literature review, or even designing experiments?

  • Could this accelerate—not replace—my discovery pipeline?

Whether you're skeptical, curious, or already experimenting with AI in your lab—this is a session designed to ground your understanding in evidence, not speculation.

  • Smarter trial design: Choose endpoints regulators accept that reflect real patient benefit.
  • Fewer amendments, faster cycles: Evidence-backed cohorts/endpoints reduce rework.
  • Regulatory confidence: Every endpoint and association links to its original source.
  • Objective benchmarks: Heterogeneous trial data becomes a fair, normalized comparison.
  • Reusable asset: A curated corpus supports multiple autoimmune programs and adjacent indications.

Traditional KG

  • Smarter trial design: Choose endpoints regulators accept that reflect real patient benefit.
  • Fewer amendments, faster cycles: Evidence-backed cohorts/endpoints reduce rework.
  • Regulatory confidence: Every endpoint and association links to its original source.
  • Objective benchmarks: Heterogeneous trial data becomes a fair, normalized comparison.
  • Reusable asset: A curated corpus supports multiple autoimmune programs and adjacent indications.

Polly KG

Register now
Meet the Expert of this discussion
Devan Moodley
Head of Translational Sciences (ex-Abata)
Sachin Gupta
Senior Scientific Manager, Elucidata
Key Takeaways
How data providers ensure adherence to quality standards through validation and compliance.
How GUI-based workflows, CLI tools, and collaborative workspaces enable streamlined data ingestion and synchronization at scale.
Understand how automated pipelines assess conformance, plausibility, and consistency, ensuring high-quality, AI-ready data products.
Key Takeaways
Reduce operational costs by streamlining data delivery through reusable, governed products.
Accelerate diagnostic development and clinical trial execution by delivering compliant, high-quality data at scale.
Improve audit readiness and regulatory confidence through governed data products and built-in quality assurance.
Equip cross-functional teams to act on trusted data—faster, and with greater confidence.
Who Should Attend
Translational Scientists and Discovery Leads
Computational Biologists and Data Scientists
Platform Owners, heads of R&D IT
Innovation and AI Strategy Teams
What Sets polly KG Apart
First KG to integrate molecular data alongside patient data records
Feature distillation pipeline for high-dimensional clinical and trial data
Base KG usable immediately, with flexible schema extensions
Cross-species graphs built from proprietary, public, and clinical datasets
Who Should Attend?

All Webinars