CASE STUDY

Elucidata Delivers 100% Automated AAV Genome Sequencing Pipelines at 4X Lower Costs

Key Highlights

  • A US-based biopharmaceutical company specializing in RNA-targeted therapeutics collaborated with Elucidata to optimize its AAV-genome sequencing process, focusing on building custom pipelines to analyze in-house virion sequencing samples and ensure cassette quality.
  • The company faced challenges in building and managing AAV-genome sequencing analysis pipelines due to limited bioinformatics expertise, making it difficult to develop pipelines for contamination detection.
  • By offering advanced customization, precision, and quality control, Elucidata provided a solution that allowed the customer to independently manage and analyze in-house sequencing data with minimal external support.
  • Elucidata developed customized, scalable pipelines for DNA Contamination Detection, deployed on the customer’s AWS infrastructure. This solution improved plasmid purity estimation accuracy by 1,000-fold, automated the process end-to-end, and reduced pipeline development costs by 4X.
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