Polly delivers the highest quality Microarray Datasets to fit diverse analysis methods and pipelines. All datasets are Polly Verified, i.e. harmonized with a configurable, granular, and transparent curation process.
Customize the processing pipeline used, metadata fields annotated, or ontologies applied to fit unique analysis needs.
Request additional curation of cohort-based comparisons within microarray datasets. Every comparison comprises pre-computed differential expression results to streamline your search for biologically relevant signatures.
Our experts implement ~50 QA checks to perform batch effect correction, metadata validation, and remove technical artifacts & variations in every dataset.
The data normalization methods or QC metrics used on Polly are not a black box. Learn how each Microarray dataset was processed by downloading a detailed QA/QC report from your Atlas on Polly.
Perform gene, pathway, or metadata-based queries to find and explore the data you need.
Utilize interactive volcano plots, heatmaps, and more to visualize enriched genes and pathways.
Stream Polly harmonized microarray datasets to your preferred tools for advanced analyses.
We use at least 50+ QA checks to ensure every dataset is:
Data validation checks ensure that all dataset and sample-level metadata annotations contain non-NULL and non-blank values.
Rigorous QC checks to ensure metadata attributes are human-readable and accurately assigned at all levels (dataset, cell).
Normalization and batch Effect correction are applied wherever necessary to eliminate technical variations and enable meaningful comparisons between samples.
Doublets, which can arise during sample preparation and confound analysis, are identified and removed.
Poor-quality samples, genes, and probes are filtered out. Genes that drive biological variation are retained and used for downstream analyses.