CASE STUDY

Integrated Metabolomics and Transcriptomics Profiling

Key Highlights

  • Targeting of metabolic pathways is a new approach for modulating immune cell function and polarization states.
  • The fate of glucose and glutamine for T-cell function was investigated to observe changes induced in T cells upon TCR stimulation. 
  • Carbon tracing and systems biology approaches integrating metabolomic and transcriptomic profiling data were used here.

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